Pregnancy with Systemic Lupus Erythematosus with Sjogren Syndrome and intrauterine fetal heart block: A successful pregnancy outcome: A case report:


Naima Sharmin Hoque1 , A T M Tanvir2 , Nurun Nahar Fatema3 , Mohammad Shakhawat Alam4 , Shariful Islam Seraji5


Fertility is not impaired with autoimmune diseases. Pregnant women with autoimmune diseases, are likely toexperience more complications than are women without the disease. Pregnancies complicated by these disordershave a high clinical impact on both the pregnancy and the disease. Sjögren syndrome is an autoimmune disease witha high prevalence of anti-SS-A (anti-Ro) and anti-SS-B (anti-La) antibodies. Anti-SS-A antibodies are associatedwith congenital heart block. Women with Primary Sjögren syndrome require prenatal counseling explaining the risksinvolved and the need to control the disease well before conception. High-risk pregnancies can be optimally managedby a multidisciplinary team. Excessive fetal morbidity and mortality have been noted in patients with systemic lupuserythematosus (SLE). The influence of anti-SSA/Ro antibodies on fetal outcome in SLE patients has rarely beenreported, but its high association with congenital heart block or neonatal lupus syndrome is well known. Here we arepresenting a case Mrs. Tahiya, 34 years, 2nd gravida with 37+wks pregnancy with SLE with Sjogren Syndrome withuncontrolled DM with history of previous 1 LSCS. This case was managed in multidisciplinary approach.

Keywords: SLE (Systemic Lupus Erythromatosus), Sjogren syndrome, anti-SS-A(anti-Ro) antibody, anti- SS-B (anti-La) antibodies, Lupus anti-coagulant.

  1. Associate Professor, Department of Obstetrics and Gynaecology

    Z H Sikder Women's Medical College, Dhaka

  2. Associate Professor (Rheumatology)

    Green life Medical College and Hospital, Dhaka

  3. Professor (Brig. General) and Paediatric and Neonatal Interventional Cardiologist

    Lab Aid Cardiac Hospital, Dhaka

  4. Associate Professor, Department of Paediatric Cardiology and Neonatology

    Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka

  5. Assistant Professor, Department of Anaesthesiology

    Holy Family Red Crescent Medical College Hospital, Dhaka

Volume 6, Number 1, January 2024
Page: 40-43